AACI Update | November 2020

Headlines

IU Simon Comprehensive Cancer Center Names New Director

IU Simon Comprehensive Cancer Center Names New Director

Indiana University School of Medicine has announced the hiring of Kelvin Lee, MD, to lead the Indiana University Melvin and Bren Simon Comprehensive Cancer Center, bolstered by a $15 million fund established by the Walther Cancer Foundation to support him in this role.

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Director Appointed for University of Illinois Cancer Center

Director Appointed for University of Illinois Cancer Center

Jan Kitajewski, PhD, has been appointed director of the University of Illinois (UI) Cancer Center effective November 13, 2020. He has served as interim director since December 2019 and joined UI Cancer Center in 2016 from Herbert Irving Comprehensive Cancer Center.

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Permanent Director Selected for WVU Cancer Institute

Permanent Director Selected for WVU Cancer Institute

Hannah Hazard-Jenkins, MD, associate chair of surgery for cancer services and a native West Virginian, has been named the permanent director of the WVU Cancer Institute after having served in the position on an interim basis since January.

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Virtual AACI/CCAF Annual Meeting Attracts Record Registrations

Virtual AACI/CCAF Annual Meeting Attracts Record Registrations

The coronavirus pandemic has challenged the cancer research community in countless ways, and the 2020 AACI/CCAF Annual Meeting was no exception. Held virtually for the first time during two days in October, the event drew nearly 900 cancer center colleagues for presentations on topics ranging from cancer screening guidelines and managing change in clinical trials to pediatric oncology and end-of-life care.

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CRI Update: Abstract Book Available, CTO Medical Director Roundtable Planned

CRI Update: Abstract Book Available, CTO Medical Director Roundtable Planned

AACI's Clinical Research Innovation (CRI) has published a digital book of abstracts and posters from the 12th Annual AACI CRI Meeting. The book features 77 abstracts from 31 cancer centers submitted for virtual presentation at the CRI meeting this past July. The CRI Clinical Trials Office (CTO) Medical Director Working Group will host a virtual roundtable on Tuesday, November 10. The discussion will focus on the results of a recent survey distributed to CTO medical directors.

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New Presidential Initiative to Focus on Mitigating Cancer Disparities

New Presidential Initiative to Focus on Mitigating Cancer Disparities

At the 2020 AACI/CCAF Annual Meeting, AACI President Karen E. Knudsen, MBA, PhD, announced plans for her presidential initiative, which will leverage the expertise of North America's 102 leading cancer institutes to address cancer health disparities. Through a two-phase process, the initiative will convert understanding of cancer disparities across AACI cancer centers into meaningful, measurable actions to improve the lives of people with cancer.

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AACI Expands Public Policy Resource Library to Track Federal Legislation

AACI Expands Public Policy Resource Library to Track Federal Legislation

AACI recently launched a federal legislation tracking tool for its Public Policy Resource Library (PPRL). The legislation tracker will provide updates on the status of cancer-related bills and will track efforts by AACI and likeminded organizations to advance the legislation. The tracker will specifically highlight federal legislation that has been endorsed by AACI’s Board of Directors.

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News from the Centers

Evers Elected to National Academy of Medicine

Evers Elected to National Academy of Medicine
UK Markey Cancer Center

B. Mark Evers, MD, FACS, director of UK Markey Cancer Center, has been elected to the National Academy of Medicine. Dr. Evers was elected for his expertise on intestinal hormones and hormonal arcades in oncogenesis.

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McDonnell to Receive Komen Brinker Award

McDonnell to Receive Komen Brinker Award
Duke Cancer Institute, Duke University Medical Center

The national breast cancer organization Susan G. Komen® has announced that Donald McDonnell, PhD, is one of two breast cancer researchers named to receive the nonprofit's Brinker Award for Scientific Distinction — Komen's highest scientific honor.

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Mullett Begins Term as Commission on Cancer Chair

Mullett Begins Term as Commission on Cancer Chair
UK Markey Cancer Center

Cardiothoracic surgeon Timothy W. Mullett, MD, MBA, FACS, has started a two-year term as chair of the Commission on Cancer of the American College of Surgeons. He serves as medical director of the UK Markey Cancer Center Affiliate Network and specializes in the treatment of lung cancer.

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Ribas Elected to National Academy of Medicine

Ribas Elected to National Academy of Medicine
UCLA Jonsson Comprehensive Cancer Center

Antoni Ribas, MD, PhD, has been named to the National Academy of Medicine. He was recognized for defining the mechanistic basis of how patients respond to or develop resistance to checkpoint inhibitors and for leading multicenter clinical trials for patients with advanced melanoma.

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Tetzlaff Named President of Association of Physician Assistants in Oncology

Fox Chase Cancer Center, Temple Health

Colleen Tetzlaff, MHS, PA-C, an advanced practice clinician at Fox Chase Cancer Center, was recently named president of the Association of Physician Assistants in Oncology for 2020-2021.

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Cone Receives 2020 APSHO Award for Excellence

Cone Receives 2020 APSHO Award for Excellence
Duke Cancer Institute, Duke University Medical Center

The Advanced Practitioner Society for Hematology and Oncology (APSHO) presented the third annual Mary Pazdur Award for Excellence in Advanced Practice in Oncology to Christina Cone, DNP, APRN, ANP-BC, AOCNP®, of Duke Cancer Institute, at JADPRO Live Virtual 2020, an educational conference for oncology advanced practitioners.

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Fox Chase Receives Press Ganey 2020 Guardian of Excellence Award

Fox Chase Cancer Center, Temple Health

Press Ganey has recognized Fox Chase Cancer Center with its 2020 Guardian of Excellence Award for providing outstanding clinical performance for patients in its outpatient clinics. The award honors organizations who continually perform in the top five percent for patient experience, engagement, or clinical quality performance throughout each quarter of the award year.

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Team Receives $11.2 Million to Leverage the Microbiome Against GVHD

Team Receives $11.2 Million to Leverage the Microbiome Against GVHD
University of Michigan Rogel Cancer Center

A team of researchers from the Rogel Cancer Center received an $11.2 million grant from the National Heart, Lung and Blood Institute to study how to use the microbiome to limit complications of stem cell transplants for blood cancers and other diseases. Principal investigator is Pavan Reddy, MD.

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$11 Million Investment to Expand IU-Purdue Bioinformatics Collaboration

Indiana University Melvin and Bren Simon Comprehensive Cancer Center

The Walther Cancer Foundation will invest $11 million to advance collaborative cancer research at Indiana University and Purdue University by supporting scientists through bioinformatics. Income from the new fund will continuously support bioinformatics personnel, technology, and other tools shared by the cancer research programs at both universities. IU and Purdue will also make their own investments into the fund.

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Grant Renewal Will Support Cancer Retrovirus Research

Grant Renewal Will Support Cancer Retrovirus Research
The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute

The Ohio State University College of Veterinary Medicine and OSUCC – James have been awarded a five-year, $9.1 million renewal from the National Cancer Institute. The grant will allow principal investigator Patrick Green, PhD, and colleagues to continue studying retrovirus models of cancer.

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$8.5 Million Gift to Establish Breast Cancer Research Institute

$8.5 Million Gift to Establish Breast Cancer Research Institute
The University of Arizona Cancer Center

Ginny L. Clements has given $8.5 million to the UArizona Cancer Center to strengthen the center's breast cancer patient care and research programs. She was diagnosed with breast cancer in 1956 at the age of 15.

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Cedars-Sinai to Study Unequal Impact of COVID-19 on Minorities

Cedars-Sinai Cancer

Cedars-Sinai has been awarded a five-year, $8.3 million grant by the National Cancer Institute to study the diversity and determinants of the immune-inflammatory response to SARS-CoV-2, the virus that causes COVID-19. Using comprehensive longitudinal data collection and analyses, the research will focus on the ethnically and racially diverse population served by the Cedars-Sinai Health System in Los Angeles.

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Mount Sinai Part of New NCI Serological Sciences Network

The Tisch Cancer Institute at Mount Sinai

Researchers from the Icahn School of Medicine at Mount Sinai will receive more than $7.3 million from the National Cancer Institute as part of its new Serological Sciences Network, one of the largest coordinated national efforts to study immunology and SARS-CoV-2, the virus that causes COVID-19.

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$7.2 Million Grant for Cancer Prevention Trials

University of Michigan Rogel Cancer Center

With a new $7.2 million grant from the National Cancer Institute, Rogel Cancer Center researchers and their national collaborators will test whether blocking inflammatory processes could protect cells and potentially prevent some cancers.

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$7 Million Grant Renewal Supports Cancer Drug Research Based on Natural Compounds

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute

OSUCCC – James and the Ohio State College of Pharmacy have been awarded a five-year, $7 million grant renewal from the National Cancer Institute. This grant will allow research to continue on potential anticancer drug leads based on compounds from tropical plants, coastal lichens, cultured cyanobacteria, and filamentous fungi.

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NCI Funds Investigation of Relationships Between HIV, Lung Cancer in East Africa

Case Comprehensive Cancer Center

Researchers with the Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have secured $4 million in funding from the National Cancer Institute (NCI) to establish an HIV-associated Malignancy Research Center focused on lung cancer in East Africa.

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Dasgupta Earns NIH Director's New Innovator Award

Dasgupta Earns NIH Director's New Innovator Award
Roswell Park Comprehensive Cancer Center

Subhamoy Dasgupta, PhD, has received a five-year, $2.52 million grant from the National Institutes of Health to support investigations into how communication channels between a cancer cell’s nucleus and the mitochondria are driving cancer metastasis. The award is part of the NIH’s High-Risk, High-Reward Research Program.

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$1.6 Million Awarded for Rutgers Youth Enjoy Science Program

Rutgers Cancer Institute of New Jersey

Rutgers Cancer Institute of New Jersey has received a $1.6 million, five-year grant from the National Cancer Institute to support the Rutgers Youth Enjoy Science (RUYES) Program. RUYES seeks to increase the diversity of the biomedical, cancer research workforce in order to reduce cancer disparities in both New Jersey and across the United States.

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Grant to Fund COVID-19 Research in Patients With Hematologic Cancers

Yale Cancer Center, Yale School of Medicine

The National Institutes of Health has awarded a Research Project Cooperative Agreement grant to Yale Cancer Center. The two-year, $1.4 million U01 award will fund immuno-serological assays for monitoring COVID-19 in patients with hematologic malignancies.

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Felsher Receives NCI Outstanding Investigator Award

Stanford Cancer Institute

Dean W. Felsher, MD, PhD, is a 2020 recipient of the National Cancer Institute's (NCI) Outstanding Investigator Award. His lab will target the MYC oncogene pathway to treat human cancer using recent fundamental insights into how MYC initiates and maintains tumorigenesis.

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Breast Cancer and Radiation Researcher Joins Mays

Mays Cancer Center, UT Health San Antonio

David Gius, MD, PhD, a breast cancer and radiation researcher, has joined the Mays Cancer Center. He was recruited from the Robert H. Lurie Comprehensive Cancer Center of Northwestern University with a $6 million senior investigator recruitment grant from the Cancer Prevention and Research Institute of Texas.

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Dinan Named Co-Leader of Cancer Prevention and Control Research Program

Dinan Named Co-Leader of Cancer Prevention and Control Research Program
Yale Cancer Center, Yale School of Medicine

Michaela A. Dinan, PhD, has been appointed co-leader of the Cancer Prevention and Control Research Program at Yale Cancer Center beginning January 1, 2021. She joins Yale from Duke Cancer Institute/Duke Clinical Research Institute.

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Director of Gastrointestinal Oncology Program Appointed

Director of Gastrointestinal Oncology Program Appointed
The Tisch Cancer Institute at Mount Sinai

Deirdre J. Cohen, MD, MS, has joined Mount Sinai Health System as director of the Gastrointestinal Oncology Program and medical director of the Cancer Clinical Trials Office at The Tisch Cancer Institute.

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Mesa Elevated to Executive Director

Mesa Elevated to Executive Director
Mays Cancer Center, UT Health San Antonio

Ruben Mesa, MD, FACP, has been named executive director of the Mays Cancer Center. The appointment broadens Dr. Mesa's scope of responsibility in coordinating and integrating all aspects of cancer prevention, screening, care, and survivorship with practice, education, and research across UT Health San Antonio.

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Park to Lead Hematology and Oncology

Park to Lead Hematology and Oncology
Vanderbilt-Ingram Cancer Center

After serving as interim director since January 1, Ben Ho Park, MD, PhD, has been named director of the division of hematology and oncology at Vanderbilt University Medical Center. He is associate director for translational research, co-leader of the breast cancer research program, and director of precision oncology at Vanderbilt-Ingram Cancer Center.

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Gerson to Serve as Interim Dean for Additional Year

Gerson to Serve as Interim Dean for Additional Year
Case Comprehensive Cancer Center

Case Western Reserve University School of Medicine Interim Dean Stanton L. Gerson, MD, has agreed to extend his term for another year, to June 30, 2022. Dr. Gerson is a Distinguished University Professor, longtime director of the Case Comprehensive Cancer Center, and a past president of AACI.

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Chief Academic Officer, Senior Director of Basic Science Named

Chief Academic Officer, Senior Director of Basic Science Named
Huntsman Cancer Institute, University of Utah

Brad Cairns, PhD, has accepted an appointment as chief academic officer at Huntsman Cancer Institute. In addition, Alana Welm, PhD, has accepted an appointment as senior director of basic science, a role previously held by Dr. Cairns.

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Winkfield to Direct Meharry-Vanderbilt Alliance

Winkfield to Direct Meharry-Vanderbilt Alliance
Vanderbilt-Ingram Cancer Center

Karen Winkfield, MD, PhD, associate director for Community Outreach and Engagement and director of the Office of Cancer Health Equity at Wake Forest Baptist Comprehensive Cancer Center, has been named the new executive director of the Meharry-Vanderbilt Alliance.

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Researchers Seek to End Unexpected Bills for Screening Colonoscopies

Researchers Seek to End Unexpected Bills for Screening Colonoscopies
University of Virginia Cancer Center

Nearly 1 in 8 commercially insured patients nationwide who underwent an elective colonoscopy between 2012 and 2017 performed by an in-network provider received "surprise" bills for out-of-network expenses, often totaling hundreds of dollars or more, new analysis from a team led by James M. Scheiman, MD, shows.

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New Discovery Could Help Improve Cancer Vaccines

New Discovery Could Help Improve Cancer Vaccines
Siteman Cancer Center

A broad collaboration of scientists co-led by Robert Schreiber, PhD, has identified five features of neoantigens that optimize the ability to trigger T cells to attack cancer and leave healthy tissue untouched. The discovery could improve immunotherapies against the disease.

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Risk of Deadly Skin Cancer May Be Gauged by Accumulated DNA Damage

Risk of Deadly Skin Cancer May Be Gauged by Accumulated DNA Damage
UCSF Helen Diller Family Comprehensive Cancer Center

Risk for melanoma can be estimated long before detection of any suspicious moles, according to A. Hunter Shain, PhD, who led a new study to detect DNA mutations in individual skin cells. The genomic methods used to probe skin damage in the study could be developed to be used to estimate baseline melanoma risk for individuals in the general population.

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Study Finds Cancer Mutations Accumulate in Distinct Regions Based on Structure of Genome, Mutational Causes

The University of Texas MD Anderson Cancer Center

A new study from The University of Texas MD Anderson Cancer Center has discovered that mutations found in cancers do not accumulate randomly, but are found in distinct patterns that vary based on the three-dimensional organization of the genome in the cell as well as the underlying factors causing the mutations.

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Experimental Drug Being Developed to Thwart Pancreatic Cancer, Other KRAS-Driven Tumors

Experimental Drug Being Developed to Thwart Pancreatic Cancer, Other KRAS-Driven Tumors
VCU Massey Cancer Center

In his previous role at Moffitt Cancer Center, Said Sebti, PhD, and colleagues discovered FGTI-2734, a drug that overcomes a major hurdle in halting the growth of malignant tumors driven by the KRAS protein, including pancreatic cancer. In collaboration with VCU Massey Cancer Center researchers, Dr. Sebti intends to further develop FGTI-2734 to eventually gain FDA approval for testing the drug in clinical trials.

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Study Shows Increased Failure-Free Survival in Prostate Cancer

Winship Cancer Institute of Emory University

A study from Winship Cancer Institute of Emory University has the potential to change how patients whose prostate cancer recurs after prostatectomy are treated. The Emory Molecular Prostate Imaging for Radiotherapy Enhancement, or EMPIRE-1, trial is the first randomized trial of men with prostate cancer with recurring cancer to show that treatment based on advanced molecular imaging can improve disease-free survival rates.

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Research Finds Anticancer Drugs Also Effective Against Epstein-Barr Virus-Related Cancers

University of Florida Health Cancer Center

University of Florida Health researchers Sumita Bhaduri-McIntosh, MD, PhD, and Michael McIntosh, PhD, and their collaborators have published new research showing a class of drugs used to treat a limited set of breast and ovarian cancers are also effective against cancers linked to the Epstein-Barr virus when tested on human cells.

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Study: Personalized Cancer Therapy Improves Outcomes in Advanced Disease

Study: Personalized Cancer Therapy Improves Outcomes in Advanced Disease
UC San Diego Moores Cancer Center

Patients receiving care for advanced cancer at Moores Cancer Center at UC San Diego Health were more likely to survive or experience a longer period without their disease progressing if they received personalized cancer therapy, report University of California San Diego School of Medicine researchers led by Razelle Kurzrock, MD.

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Biomarker Found That Can Appear Before Stomach Cancer Develops

Biomarker Found That Can Appear Before Stomach Cancer Develops
The University of Arizona Cancer Center

A promising new biomarker that appears in patients before stomach cancer develops may help with early detection of the disease and improve patient response to therapy, according to findings in a study led by Juanita L. Merchant, MD, PhD, and colleagues at the University of Arizona Health Sciences.

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CAR NKT Cells Offer a Promising Novel Immunotherapy for Solid Tumors

Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine

Researchers at Baylor College of Medicine and the University of North Carolina at Chapel Hill have genetically modified human Natural Killer T (NKT) cells with a chimeric antigen receptor (CAR) that enables them to specifically recognize and attack neuroblastoma. Expressed with the CAR is interleukin-15 (IL-15), a natural protein that supports NKT cell survival.

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Immunotherapy Trial in Advanced Bladder and Other Urinary Tract Cancers Shows Results

Immunotherapy Trial in Advanced Bladder and Other Urinary Tract Cancers Shows Results
Fred Hutchinson Cancer Research Center

In a large randomized clinical trial, researchers evaluated the immunotherapy drug avelumab for patients with advanced urothelial cancer. And the findings of the trial, called the JAVELIN Bladder 100 study, are "practice-changing," according to Petros Grivas, MD, PhD, of Fred Hutchinson Cancer Research Center, who is the co-leader of this global, industry-sponsored trial.

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Tool Developed to Better Predict Treatment Course for Lung Cancer Patients

Moffitt Cancer Center

For patients with non-small cell lung cancer, two major treatment strategies have emerged: tyrosine kinase inhibitors and immune checkpoint inhibitors. However, choosing the right therapy isn’t always an easy decision, as biomarkers can change during therapy rendering that treatment ineffective. Moffitt Cancer Center researchers are developing a noninvasive, accurate method to analyze a patient’s tumor mutations and biomarkers to determine the best course of treatment.

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Virus-Mimicking Drug Helps Immune System Target Cunning Cancer Cells

UCLA Jonsson Comprehensive Cancer Center

Researchers at the UCLA Jonsson Comprehensive Cancer Center have found that a drug that activates the body’s natural defenses by behaving like a virus may also make certain stealthy melanoma tumors visible to the immune system, allowing them to be better targeted by immunotherapy.

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Axing the ACA Means Young Adults With Cancer Lose Coverage

UCSF Helen Diller Family Comprehensive Cancer Center

A new study by UCSF Benioff Children’s Hospitals and the Children’s Hospital of Philadelphia has quantified the impact of repealing the 2010 Affordable Care Act (ACA), which enables 18- to 25-year-olds to remain on their parents insurance plans, including cancer patients who require long-term medical follow-up. The study builds on previous UCSF research showing that children covered by private health insurance have better outcomes than those who are not.

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Molecular Shape Shifters

University of New Mexico Comprehensive Cancer Center

Peng Mao, PhD, and his team have discovered an intricate series of events that cells use to repair DNA, finding that in transcription-coupled DNA repair, RNA polymerases change shape when one type of protein binds and dislodges other proteins. The shape change switches RNA polymerase from transcribing DNA to repairing.

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Opioid Use Among Cancer Patients

Opioid Use Among Cancer Patients
The University of Kansas Cancer Center

Opioids for pain relief are often a necessity for cancer patients, but opioid use comes with its own set of risks. Two papers published by researchers at The University of Kansas Cancer Center bring those risks to light. Using the National Cancer Institute’s Surveillance, Epidemiology, and End Results-Medicare database, Andrew Roberts, PharmD, PhD, and his team conducted two retrospective studies.

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Not All Patients Are Offered the Same Effective Breast Cancer Treatment

Sidney Kimmel Cancer Center at Jefferson Health

Breast cancer is one of the most common cancers among women and the most costly to treat. Now, Jefferson researchers have shown that although the use of an effective and less expensive treatment is on the rise, some patients, specifically Black women and those without private insurance, are offered the beneficial therapy less often.

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UVA Improves Care for Cancers That Have Spread to the Brain

University of Virginia Cancer Center

Ambitious efforts at the UVA Cancer Center to improve care delivered to patients with cancer that has spread to the brain have yielded important insights and tools that can benefit other hospitals, a new publication reports. The tools include the first set of metrics to assess care provided for these secondary tumors, known as brain metastasis.

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Activating Inflammasome May Improve Cancer Response to Immunotherapy and PARP Inhibitors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University

The inflammasome—a protein signaling network that is activated to rid the body of virus or bacteria-infected cells—may play an important role in triggering an immune response to cancer and causing an existing class of drugs to work better against cancers. A collaborative research study led by experts at the Johns Hopkins Kimmel Cancer Center and University of Maryland Marlene and Stewart Greenebaum Cancer Center, supported by Stand Up To Cancer and the Adelson Medical Research Foundation, found that the inflammasome imparts a DNA repair defect-like state in cancer cells.

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Changing Gut Microbiota, Taming Inflammation May Help Battle Colorectal Cancer

University of Florida Health Cancer Center

Colon cancer may be treated or even prevented by altering microorganisms in the intestine and by combating inflammation with a clinical treatment previously used to treat inflammatory bowel diseases, findings from a study led by the University of Florida suggest.

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Genomic Differences May Be Key to Overcoming Prostate Cancer Disparities Among African-American Men

Moffitt Cancer Center

Moffitt Cancer Center researchers are taking a closer look at the genomic features of prostate cancer tumors among men of different races in hopes of better understanding why African Americans are more susceptible to the disease. In a new study, the research team describes the immune-oncologic differences in prostate cancer tumors of African-American men and how those variations may be exploited to develop more personalized treatment approaches for this population.

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New Strategy for Overcoming Resistance to Immunotherapy Unleashes Power of Dendritic Cells

New Strategy for Overcoming Resistance to Immunotherapy Unleashes Power of Dendritic Cells
Roswell Park Comprehensive Cancer Center

Many of the most aggressive and hard-to-treat cancers are highly effective at blocking T cells from reaching and responding to tumors. But research led by Fumito Ito, MD, PhD, FACS, and Roswell Park Comprehensive Cancer Center colleagues details a new strategy for overcoming this resistance by zeroing in on dendritic cells and enhancing their function as "accessory cells" supporting other immune cells.

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Sexual Health Often Overlooked in Cancer Survivorship Care, Especially for Women

Sidney Kimmel Cancer Center at Jefferson Health

A new study points to a need for oncologists to ask their patients about sexual health after chemotherapy, radiation, and other cancer treatments. In a survey of nearly 400 cancer survivors, 87 percent said they experienced sexual side effects, but most also said their oncologist had not formally asked about them. Female patients were especially unlikely to be asked about sexual dysfunction.

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Social Media Policies Can Curb HPV Vaccine Misinformation, Improve Public Health Communications

Social Media Policies Can Curb HPV Vaccine Misinformation, Improve Public Health Communications
VCU Massey Cancer Center

A new study led by VCU Massey Cancer Center researcher Jeanine Guidry, PhD, compared how HPV vaccination was portrayed on Pinterest before and after the social media platform began moderating vaccine-related content. Findings may help public health officials utilize social media to tackle potentially harmful rhetoric and disseminate trustworthy health information.

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Study Shows How HIV and Cancer Drugs Accelerate Cellular Aging

Study Shows How HIV and Cancer Drugs Accelerate Cellular Aging
UPMC Hillman Cancer Center

A new study led by researchers at UPMC Hillman Cancer Center and the University of Pittsburgh shows for the first time how certain drugs used to treat HIV and cancer drive the cellular aging process, at least in part, by blocking telomeres from replenishing themselves. Patty Opresko, PhD, is senior author on the study.

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Study Documents Racial Differences in U.S. Hospice Use and End-of-Life Care Preferences

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University

In a new medical records analysis of racial disparities in end-of-life care, researchers at Johns Hopkins Medicine and three collaborating institutions report that Black patients voluntarily seek substantially more intensive treatment, such as mechanical ventilation, gastronomy tube insertion, hemodialysis, CPR, and multiple emergency room visits in the last six months of life, while white patients more often choose hospice services.

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AI Tool Created to Guide Colorectal Cancer Care With More Precision

Stanford Cancer Institute

A new modeling tool may be able to help doctors assess which treatments are best for individual patients with colorectal cancer. The artificial intelligence program analyzes a patient's disease details—such as the stage of cancer and other chronic conditions—and compares those details to other colorectal cancer cases to predict the patient's chance of surviving past 10 years.

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Assessing Diversity in Cancer Center Leadership

Results from a leadership diversity survey conducted by AACI in partnership with The Cancer Letter (TCL) show that there’s a long road ahead in confronting cancer disparities in the oncology leadership pipeline. In an editorial published in the October 9 edition of TCL, AACI President Karen E. Knudsen, MBA, PhD, and Immediate Past President Roy A. Jensen, MD, shared their thoughts on the survey results.

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Cancer Compound Leads to Licensing Deal

Cancer Center at Illinois

Researchers affiliated with the Cancer Center at Illinois discovered a novel small molecule compound that is now the subject of a new global licensing agreement between the pharmaceutical company Bayer AG and the cancer drug development company Systems Oncology LLC.

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Investment Fund Launched to Support Promising Investigational Cancer Therapies

The University of Texas MD Anderson Cancer Center

The Focus Fund GP, LLC, in partnership with The University of Texas MD Anderson Cancer Center, has launched Cancer Focus Fund, LP, an oncology-focused investment fund designed to support the advancement of compelling investigational cancer therapies from late preclinical development through Phase I and Phase Ib/II clinical trials.

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Cancer Center Jobs

Director, Clinical Trials Office
University of New Mexico Comprehensive Cancer Center
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Director, Cancer Center
The University of Vermont Cancer Center
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Director, Sanford Burnham
Sanford Burnham Prebys Medical Discovery Institute
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Senior Director, Clinical Operations and Compliance
University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center
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Chief Operating Officer, Indiana Clinical and Translational Sciences Institute
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
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Assistant Professor of Oncology
Livestrong Cancer Institutes, The University of Texas at Austin, Dell Medical School
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Informatics Project Manager
UCI Chao Family Comprehensive Cancer Center
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Sponsored Programs Administrator
UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
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Meeting Announcements

2020 SITC Annual Meeting

November 9, 2020
Virtual Meeting
Registration is now open for the Society for Immunotherapy of Cancer’s 35th Anniversary Annual Meeting and Pre-Conference Programs (SITC 2020), a fully virtual experience, taking place online over new dates, November 9-14, 2020. In celebration of the society’s 35th anniversary, all SITC members are invited to register for free. 
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