AACI Update | January 2026

Headlines

AACI Welcomes UMass Memorial Health Cancer Center

AACI Welcomes UMass Memorial Health Cancer Center

AACI is pleased to announce that UMass Memorial Health (UMMH) Cancer Center became the association's newest member in December 2025. UMMH Cancer Center is led by David Cachia, MD, interim chief of Hematology Oncology Services and associate professor of neuro-oncology at the University of Massachusetts.

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Call for Abstracts: 18th Annual AACI CRI Meeting

Call for Abstracts: 18th Annual AACI CRI Meeting

The AACI Clinical Research Innovation (CRI) Steering Committee is currently soliciting abstracts for the 18th Annual AACI CRI Meeting. This year’s meeting theme is "Shaping the Future of Clinical Trial Innovation." The purpose of the abstracts is to inform attendees about challenges and solutions implemented at AACI cancer centers, showcasing advancements across key areas in clinical research and operational excellence.

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CADEx Spotlight: Bringing Data and People Together in Clinical Research

CADEx Spotlight: Bringing Data and People Together in Clinical Research

"Bringing Data and People Together in Clinical Research" will focus on practical ways to use catchment area data to ensure that clinical trial enrollment reflects both the broader population and specific neighborhoods. The session is scheduled for 9:00 am eastern time on Wednesday, March 11.

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Place an Ad in the AACI Newsletter

AACI invites you to promote your cancer center or company by purchasing an ad in the AACI Update. Your ad may highlight a conference, new initiative, or product of interest to AACI members. In addition to newsletter ads, AACI offers a variety of support opportunities for its annual events. For more information about supporting AACI, please contact Development Manager Chelsea Borries.

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AACI Launches New Cancer Service Line Listserv

AACI is pleased to announce the launch of a new Cancer Service Line listserv. This new platform offers an additional space for members to connect, share best practices, and exchange insights. All AACI members who work with service lines are welcome to participate. Subscribers must have a valid cancer center email address to join.

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News from the Centers

Giuliano Honored With McGuire Memorial Award

Giuliano Honored With McGuire Memorial Award
Cedars-Sinai Cancer

Armando E. Giuliano, MD, received the William L. McGuire Memorial Lecture Award in December at the San Antonio Breast Cancer Symposium, in recognition of his development of the sentinel lymph node technique, transforming surgical management of breast cancer.

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Pediatric Oncology Researcher Elected to National Academy of Inventors

Pediatric Oncology Researcher Elected to National Academy of Inventors
Indiana University Melvin and Bren Simon Comprehensive Cancer Center

Mark R. Kelley, PhD, senior leader for biomedical innovation and partnerships at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center, has been named a 2025 fellow of the National Academy of Inventors for his contributions to pediatrics and cancer research.

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A Scientist Without Borders Steps Onto the National Stage

A Scientist Without Borders Steps Onto the National Stage
Fox Chase Cancer Center, Temple Health

Edna "Eti" Cukierman, PhD, was recently appointed to the National Cancer Institute’s Working Group for Extramural Research Concepts, an advisory group that brings together 35 national experts to help shape the direction of federally supported cancer research.

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Breast Cancer Researcher Elected to National Academy of Inventors

Breast Cancer Researcher Elected to National Academy of Inventors
UCLA Jonsson Comprehensive Cancer Center

Dennis Slamon, MD, PhD, whose innovations in breast cancer treatment have benefited millions around the globe, was named to the 2025 class of the National Academy of Inventors.

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Designation Announced for NORD Rare Disease Center of Excellence

The University of Kansas Cancer Center

The University of Kansas Medical Center, Children’s Mercy, and the University of Kansas Health System have collectively been designated a NORD Rare Disease Center of Excellence by the National Organization for Rare Disorders (NORD). The NORD Rare Disease Centers of Excellence Network now includes 46 institutions across 28 states and Washington, DC.

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$30 Million Gift to Improve Access to Rural Health Care

Mays Cancer Center at UT Health San Antonio MD Anderson

The University of Texas at San Antonio has announced a $30 million gift from the Kate Marmion Charitable Foundation to support the mission of The University of Texas at San Antonio School of Public Health and improve the health and well-being of communities across South Texas.

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$30 Million Gift Creates BRCA Center

Cedars-Sinai Cancer

Cedars-Sinai has received a $30 million gift from the Cayton Goldrich Family Foundation to establish the Cedars-Sinai Cayton BRCA Center. The state-of-the-art center will concentrate on the research, diagnosis, and comprehensive treatment of illnesses linked to mutations in the genes known as BRCA1 and BRCA2.

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UAMS Awarded $10.5 Million as Nationwide Hub to Develop Biomarkers for Human Diseases Including Cancer

UAMS Winthrop P. Rockefeller Cancer Institute

The University of Arkansas for Medical Sciences (UAMS) has received a five-year, $10.5 million grant from the National Institutes of Health (NIH) to develop biomarkers for all human diseases including cancer through the IDeA National Resource for Quantitative Proteomics. The grant supports ongoing efforts to make highly advanced protein analysis known as proteomics available to biomedical researchers nationwide.

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$7.5 Million for Tobacco Cessation

$7.5 Million for Tobacco Cessation
Siteman Cancer Center

Li-Shiun Chen, MD, and other WashU Medicine researchers at Siteman Cancer Center have received $7.5 million for a multicenter trial aimed at developing effective tobacco-treatment strategies in cancer clinics.

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BCRF Awards $2.6 Million in Grants

Fred Hutch Cancer Center

Seven scientists with the Fred Hutch Cancer Center/University of Washington/Seattle Children’s Cancer Consortium received another year of funding from the Breast Cancer Research Foundation, or BCRF, to pursue research into new therapies, new biomarkers, and new vaccines meant to improve outcomes in this deadly disease.

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Research Seeks to Unlock Pancreatic Cancer Mysteries With $1.8 Million NCI Grant

UMMC Cancer Center and Research Institute

Inside the labs at the Cancer Center and Research Institute at the University of Mississippi Medical Center, researchers are studying how a protein that’s been in humans since the embryonic stage plays a role in triggering the development of a particularly deadly type of pancreatic cancer. The project, in the second year of a five-year $1.8 million grant from the National Cancer Institute (NCI), could lead to better biomarkers for the disease and improved treatment.

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Grant Awarded to Advance Childhood Cancer Research

Mount Sinai Tisch Cancer Center

David Dominguez-Sola, MD, PhD, was awarded a St. Baldrick’s Foundation grant to support research in Burkitt lymphoma with the goal of developing more precise, less toxic treatments for children facing this aggressive cancer. Dr. Dominguez-Sola’s lab is exploring how a specific genetic mutation drives Burkitt lymphoma’s growth and how a metabolic pathway that his team discovered may be key to how the cancer spreads.

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Ghobadi Named Director of Cellular Therapies

Ghobadi Named Director of Cellular Therapies
Siteman Cancer Center

Armin Ghobadi, MD, a WashU Medicine professor of medicine and bone marrow transplant specialist, has been named director of cellular therapies at Siteman Cancer Center. The new position formalizes his role as leader of clinical care and clinical research activities related to cellular therapy in the Hematologic Malignancies program at WashU Medicine.

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Goss to Head Cancer Research Administration

Goss to Head Cancer Research Administration
The University of Chicago Medicine Comprehensive Cancer Center

Kathleen Goss, PhD, has been named executive director of cancer research administration for UChicago Medicine Comprehensive Cancer Center, effective January 5. She most recently served as senior scientific director for extramural discovery science at the American Cancer Society.

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Liekweg Named Associate Director for Administration

Liekweg Named Associate Director for Administration
University of Michigan Rogel Cancer Center

The University of Michigan Rogel Cancer Center has named Christopher J. Liekweg, MBA, CMPE, associate director for administration and chief department administrator, effective January 12. Liekweg is a senior administrator at VCU Health, the academic medical center of Virginia Commonwealth University. He was previously executive director for radiation oncology at the University of Louisville.

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Dramatic Drop in HIV-Infected Immune Cells Seen After Chemotherapy Given for Cancer in Person Living With HIV

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University

Researchers at Johns Hopkins Medicine report they may have taken an early step toward a more practical HIV cure. The study, done largely with federal funding, focused on a patient undergoing cancer treatment and also living with HIV, who, after receiving chemotherapy, had a significant reduction in the number of CD4+ T immune cells that contained an HIV provirus – a key player in HIV’s ability to persist in the body.

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New Discovery May Improve Ovarian Cancer Treatment

New Discovery May Improve Ovarian Cancer Treatment
University of New Mexico Comprehensive Cancer Center

Hua-Ying Fan, PhD, and her team at the UNM Comprehensive Cancer Center discovered that auranofin, a drug approved by the FDA, may sensitize ovarian cancer cells to standard chemotherapy treatment. They discovered that auranofin disrupts the Notch pathway, which certain ovarian cancer cells depend on for their development.

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Study Finds Childhood Leukemia Aggressiveness Depends on Timing of Genetic Mutation

Mount Sinai Tisch Cancer Center

Elvin Wagenblast, PhD, and team have uncovered why children with the same leukemia-causing gene mutation can have dramatically different outcomes, depending on when in development the mutation first occurs. Their findings show that leukemia beginning before birth is often more aggressive, grows faster, and is harder to treat.

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Link Between Tumor Metabolism, Drug Efficacy in Cancer Cells May Help Advance Precision Chemotherapy

Link Between Tumor Metabolism, Drug Efficacy in Cancer Cells May Help Advance Precision Chemotherapy
Stony Brook Cancer Center

An international research team, including Stony Brook University Distinguished Professor Peter J. Tonge, PhD, has demonstrated a connection between drug efficacy and tumor metabolism in an established target of human cancers that provides a mechanistic bridge between tumor metabolism and drug engagement in cancer cells.

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Team Discovers How to Target 'Undruggable' Protein That Fuels Aggressive Leukemia

UCLA Jonsson Comprehensive Cancer Center

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer-driving protein long considered impossible to target with drugs – a discovery that could open the door to a new class of treatments for leukemia and other hard-to-treat cancers.

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Genetic Clues Piece Together the Puzzle of Pediatric Thyroid Cancer Predisposition

Comprehensive Cancer Center St. Jude Children's Research Hospital

When a child is diagnosed with cancer, parents often want to understand why. For those with pediatric thyroid carcinoma, that question has long gone unanswered. However, a new study is changing that narrative, revealing hidden genetic clues that may help explain why the disease occurs in some children.

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Leukemia Drug Secures FDA Approval

University of Michigan Rogel Cancer Center

Komzifti (ziftomenib) has received approval from the United States Food and Drug Administration for acute myeloid leukemias (AMLs) with the NPM1 mutation. The mutation makes AML, already an aggressive disease, more difficult to treat and affects 30 percent of all AML cases. The drug was discovered and developed by researchers at the University of Michigan Health Rogel Cancer Center and Department of Pathology.

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New Research Targets Iron Dependency in Multiple Myeloma Cells

New Research Targets Iron Dependency in Multiple Myeloma Cells
Duke Cancer Institute

Multiple myeloma remains one of the most challenging hematologic malignancies to treat. Despite advances in therapy, many patients eventually relapse or develop resistance to standard treatments. A team led by Mikhail Nikiforov, PhD, a Duke Cancer Institute member, is uncovering a promising new approach that could reshape the therapeutic landscape.

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Race, Ethnicity and Donor Type Continue to Affect Survival After Donor Stem Cell Transplant

Roswell Park Comprehensive Cancer Center

A study led by Roswell Park Comprehensive Cancer Center reveals that a patient’s race and ethnicity, as well as how closely matched they are to their stem cell donor, can significantly affect clinical outcomes for those who undergo stem cell transplant as treatment for cancer – despite the introduction of a new standard-of-care drug regimen shown to lower the risk of graft-versus-host disease, a potentially fatal side effect.

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Research Links Health Impacts Related to 'Forever Chemicals' to Billions in Economic Losses

The University of Arizona Cancer Center

The negative health impacts from contamination by so-called "forever chemicals" in drinking water costs the contiguous U.S. at least $8 billion a year in social costs, a University of Arizona-led study has found. The study builds on previous research into how PFAS—per- and polyfluoroalkyl substances—can negatively impact health when the chemicals contaminate drinking water.

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Clinical Trial Using Focused Ultrasound With Chemotherapy Finds Potential Survival Benefit for Brain Cancer Patients

University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center

Patients with glioblastoma who received MRI-guided focused ultrasound with standard-of-care chemotherapy had a nearly 40 percent increase in overall survival in a landmark trial of 34 patients led by University of Maryland School of Medicine researchers.

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Differences Revealed in How Multiple Myeloma Develops in Men and Women

Indiana University Melvin and Bren Simon Comprehensive Cancer Center

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have uncovered biological differences in how multiple myeloma develops and progresses in men and in women. The rare blood cancer occurs more often in men than in women, making these biological differences important for understanding why multiple myeloma affects the sexes differently.

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Significant Mental Health Care Gaps Seen for Childhood Cancer Survivors

Winship Cancer Institute of Emory University

With rising survival rates of childhood cancers, ensuring survivors receive mental health services is essential for long-term well-being. A recent study led by Rollins School of Public Health and Emory School of Medicine researchers looked at how often childhood cancer survivors utilized mental health services after their diagnosis. The answer is: not nearly enough.

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Breakthrough Trial Shows Promising Therapy for Aggressive Brain Cancer

Huntsman Cancer Institute at the University of Utah

Huntsman Cancer Institute at the University of Utah participated in a clinical trial that found that a new combination treatment plan helped people with recurring grade 3 astrocytoma live longer. The Phase III trial evaluated the efficacy and safety of a treatment plan using a combination of the drug eflornithine, a compound that targets an enzyme to inhibit the proliferation of tumor cells, and the oral chemotherapy lomustine.

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Comprehensive Study Settles Debate Over Diet Safety for Cancer Patients

UF Health Cancer Institute

For decades, patients undergoing blood cancer treatment have been told to avoid certain foods to reduce infection risk, guidance that some physicians hoped could safely be relaxed. Now, a University of Florida study offers clear evidence that a diet designed to limit exposure to foodborne microbes results in fewer serious infections, confirming it is still the safest choice.

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Study Identifies Pathway Driving Prostate Cancer Bone Metastatic Progression

UK Markey Cancer Center

A UK Markey Cancer Center study reveals how prostate cancer cells adapt their metabolism to thrive in bone tissue, offering a potential new treatment target for patients with advanced disease. The research identifies a biological pathway that helps prostate cancer cells produce the energy they need to grow in bone.

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Cell-Free DNA Could Detect Adverse Events From Immunotherapy

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University

A noninvasive blood test to detect genetic material shed by tumors may help clinicians identify adverse events related to treatment with immune checkpoint inhibitor drugs, investigators at the Johns Hopkins Kimmel Cancer Center have found. The researchers measured cell-free DNA to identify tissue damage to nine organs in a study involving 14 patients with solid tumors who received immune checkpoint inhibitor therapy.

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Study Uncovers Immune Switch for Cancer and Autoimmunity

Stanford Cancer Institute

Stanford Cancer Institute member Edgar Engleman, MD, is the senior author on a study finding that the erythropoietin signaling pathway in type 1 conventional dendritic cells triggers regulatory T cells, essentially acting as a central switch that controls immune tolerance. Manipulating this pathway could allow researchers to toggle the immune response to treat many types of diseases, including cancers, autoimmune disorders, and those that require organ transplants.

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Next-Generation CAR T Cells Show Stronger, Safer Response in Animal Models, Study Shows

USC Norris Comprehensive Cancer Center

USC researchers have engineered a next-generation CAR T cell therapy that may provide a safer, more effective way to treat blood cancers such as leukemia and lymphoma. They did it by developing a new way to control the CAR T cell signaling process which helps guide how strongly and how long the immune cells that fight the cancer, known as T cells, stay activated.

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Researchers Identify Strategy for Reducing Risk of Acute Graft-Versus-Host Disease for Many With Blood Cancers

Roswell Park Comprehensive Cancer Center

Preclinical research from Roswell Park Comprehensive Cancer Center and the University of Minnesota demonstrates that inhibiting a particular metabolic pathway decreases the incidence and severity of a serious side effect, acute graft-versus-host disease, while preserving beneficial effects of treatment for cancer patients who receive an allogeneic hematopoietic stem cell transplant.

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Cancer-Promoting DNA Circles Hitchhike on Chromosomes to Spread to Daughter Cells

Stanford Cancer Institute

Stanford researchers identified retention elements that tether episomes to mitotic chromosomes to increase ecDNA transmission into daughter cells. Triggering the addition of methyl groups resulted in the affected ecDNAs no longer attaching to chromosomes and were significantly less likely to be portioned to daughter cells.

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Program Aims to Help Childhood Cancer Survivors as They Enter Adulthood

The University of Kansas Cancer Center

The transition to adult care may get easier for childhood cancer survivors at The University of Kansas Cancer Center, thanks to a $750,000 grant from Braden’s Hope for Childhood Cancer, a Kansas City-based nonprofit organization founded to accelerate the fight against childhood cancer. The award will fund a new Adolescent and Young Adult Cancer Transitions Program at KU Cancer Center.

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Cann Leads Effort to Transform Young Adult Cancer Care

Cann Leads Effort to Transform Young Adult Cancer Care
Fox Chase Cancer Center, Temple Health

Christopher G. Cann, MD, first found his passion for treating young adult cancer patients as a resident and fellow. Now, after receiving the Robert A. Winn Excellence in Clinical Trials: Career Development Award, he is even better equipped to work with this unique, underserved population.

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Cancer Center Jobs

Administrator - School of Medicine, Medical Oncology
Winship Cancer Institute of Emory University
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Deputy Associate Director, Community Outreach and Engagement
LSU LCMC Health Cancer Center
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Chief Medical Information Officer
Fred Hutch Cancer Center
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Associate Director for Administration
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
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Pediatric Oncology and Cellular Therapy Physician Scientist
Hollings Cancer Center, Medical University of South Carolina
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Meeting Announcements

2026 AACI Catchment Area Data Excellence (CADEx) Conference

March 9, 2026
Grand Hyatt Atlanta in Buckhead, Atlanta, GA

The 3-day CADEx conference convenes experts in cancer center catchment area data and community engagement to share best practices. Attendees will explore policies and methodologies to advance cancer center catchment area analytics.

Registration is now open.

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2026 AACI/AACR Hill Day

May 14, 2026
Hyatt Regency Washington on Capitol Hill, Washington, DC

Your participation in the 2026 AACI/AACR Hill Day is crucial to sharing our message with our legislators in Washington: that stable, predictable funds for the National Institutes of Health and National Cancer Institute are critical for advancing cancer research and care at our nation’s cancer centers. We encourage each cancer center to send at least one representative to Washington to advocate on your center’s behalf.

Registration for this free event opens Monday, March 16, 2026.

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18th Annual AACI Clinical Research Innovation (CRI) Meeting

June 23, 2026
Loews Chicago O'Hare Hotel, Rosemont, IL

The 3-day CRI annual meeting includes panel discussions, breakout sessions, and presentations of abstracts and posters, which aim to establish best practices for cancer center clinical trials offices. Registration opens Monday, March 2, 2026.

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2026 AACI Leadership Development Workshop

October 24, 2026
Marriott Chicago Downtown Magnificent Mile, Chicago, IL

The 2026 Leadership Development Workshop will be held in conjunction with the 2026 AACI/CCAF Annual Meeting. Registration opens Friday, May 1, 2026.

This event convenes emerging leaders for didactic and experiential leadership development sessions. An offshoot of Dr. Caryn Lerman’s AACI presidential initiative, the workshop aims to enhance the oncology leadership pipeline with top talent.

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2026 Impact Summit

October 24, 2026
Marriott Chicago Downtown Magnificent Mile, Chicago, IL

The 2026 Impact Summit will be held in conjunction with the 2026 AACI/CCAF Annual Meeting. Registration opens Friday, May 1, 2026.

Co-hosted by AACI, the American Cancer Society, and the Cancer Center Network, the Impact Summit brings together cancer center leaders, researchers, and key stakeholders for a dynamic one-day event focused on strengthening the future of cancer center leadership and workforce development.

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2026 New Cancer Center Directors Meeting

October 24, 2026
Marriott Chicago Downtown Magnificent Mile, Chicago, IL

The 2026 New Cancer Center Directors Meeting will be held in conjunction with the 2026 AACI/CCAF Annual Meeting. Registration opens Friday, May 1, 2026.

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2026 AACI/CCAF Annual Meeting

October 25, 2026
Marriott Chicago Downtown Magnificent Mile, Chicago, IL

The 3-day AACI/CCAF annual meeting offers AACI members the opportunity to network with cancer center colleagues, national cancer research and advocacy groups, industry, and government health agencies to develop solutions to common challenges. Registration opens Friday, May 1, 2026.

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