Theodorescu Appointed Director at Cedars-Sinai

Cancer clinician and scientist Dan Theodorescu, MD, PhD has been named director of the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai, in Los Angeles. He has served since 2010 as director of the University of Colorado Cancer Center and will assume his new post July 1.

Dr. Theodorescu, a translational cancer researcher and leading expert in bladder cancer, will bring a compelling vision to Cedars-Sinai, leading what he sees as three revolutions shaping modern cancer care: using precision medicine strategies to personalize treatments; tapping "big data" to solve difficult research and treatment questions; and, employing population health ideas to improve the lot of entire populations while reducing health inequities among groups.

At Colorado, a National Cancer Institute (NCI)-designated cancer center, Dr. Theodorescu led a statewide consortium of three universities and three academic teaching hospitals. He also has been a professor of surgery and pharmacology in the system. During his eight years he twice led the successful renewal of the centerís NCI Cancer Center Support Grant.

Dr. Theodorescu said his strong motivation to enact change began at age seven when his family emigrated from Romania to Canada. His educator parents instilled in him "a sense of unbridled optimism and a determination to seize opportunities to contribute to society," prompting his lifelong interest in scientific discoveries.

In the laboratory, Dr. Theodorescu is known for his work on the molecular mechanisms underlying bladder cancer and translating these into therapeutic approaches. He also contributed precision medicine approaches such as the CO-Expression Extrapolation, or "COXEN" tool, which personalizes cancer therapy by identifying drugs that likely will be effective in patients based on genomic characteristics of their tumors. Dr. Theodorescuís laboratory has been supported by the National Institutes of Health and other prestigious funding agencies for more than two decades.

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